UTI in Pregnancy

Send MSU for culture.

Short-term use of nitrofurantoin in pregnancy is unlikely to cause problems to the foetus. 

Trimethoprim use in pregnancy is now unlicensed.

Avoid trimethoprim if low folate status or taking folate antagonist (eg antiepileptic or proguanil).

First choice:


(avoid in 3rd trimester)


100mg m/r 2 x daily


50mg 4 x daily


7 days

Alternative treatment


(unlicensed indication -

 avoid in 1st trimester) 


200mg 2 x daily


7 days