Acute Infective Exacerbation of COPD
Treat exacerbations promptly with antibiotics if purulent sputum and increased shortness of breath and/or increased sputum volume.
Note: Use of an antibiotic is not recommended in the absence of purulent sputum.
Risk factors for antibiotic resistant organisms include co-morbid disease, severe COPD, frequent exacerbations, antibiotics in last 3 months.
Link to patient information leaflet
500mg three times daily
500mg four times daily
200mg stat then 100mg once daily
If resistance: co-amoxiclav
625mg three times daily