If abnormality of urinary tract consider longer course of 10 to 14 days.
- Samples should be taken prior to starting treatment.
- Send blood for culture if pyrexial.
Gentamicin¥ IV (Hartford Regimen) as per guideline
NB: if reduced or unstable renal function give single dose only then review with Infectious Diseases or Microbiology
PLUS Amoxicillin 1g IV 8 hourly
Switch to oral option guided by microbiology sensitivities
¥If > 72 hours IV therapy required replace gentamicin with temocillin IV 2g 12 hourly.
Ciprofloxacin 500mg oral (or 400mg IV) 12 hourly
Switch to alternative oral option if indicated by microbiology sensitivities.
NB: Nitrofurantoin is not suitable for use in pyelonephritis