Stop unnecessary antibiotics, PPIs and antiperilstaltic agents.
70% respond to MTZ in 5 days; 92% in 14 days.
If severe symptoms or signs (below) should treat with oral vancomycin, review progress closely and/or consider hospital referral.
Definition of severe: T >38.5oC, or WCC >15, or rising creatinine or signs/symptoms of severe colitis.
2nd episode/severe/type 027:
10-14 days then taper
Recurrent: Discuss with microbiology