Cellulitis - Severe
Flucloxacillin 2g IV 6 hourly +/- Gentamicin IV as per protocol
Clindamycin 450mg 6 hourly PO OR 600mg 6 hourly IV
Vancomycin IV +/- Gentamicin IV as per protocol
Clindamycin 450 mg PO 6 hourly OR 600mg IV 6 hourly
Mark boundary of cellulitis and review regularly.
Seek surgical review ASAP as clinically indicated, especially if severe pain or rapid spread / clinical deterioration despite antibiotics.
Send swabs for culture. Even if no break in skin a firm swab of most cellulitic area may yield pathogen to guide management.
Treatment duration: 7 days (may be longer depending on severity of systemic infection and clinical response)