Cellulitis - Severe of rapidly spreading

First Line

Flucloxacillin  2g IV 6 hrly +/- Gentamicin IV as per protocol

Consider adding

Clindamycin 450 mg PO 6hrly OR  600mg IV 6 hrly

Penicllin Allergy

Vancomycin IV +/- Gentamicin IV as per protocol

Consider adding

Clindamycin 450 mg PO 6hrly OR  600mg IV 6 hrly

Notes

Bilateral cellulitis is uncommon - Exclude other causes of bilateral lower limb soft tissue changes

Seek surgical review ASAP if indicated, mark area, send swabs

 

Duration of treatment depends on the clinical improvement rate