Exacerbation of Bronchiectasis

First Line

Co-amoxiclav 1.2g IV 8hrly +/- Clarithromycin (if atypical pneumonia is suspected/likely or confirmed) 500 mg 12hrly PO/ IV

If known to have Pseudomonas spp. and sensitive to

Ciprofloxacin 750mg bd PO +/- Gentamicin IV as per protocol

otherwise be guided by previous sensitivities

Penicillin Allergy

Vancomycin IV as per protocol AND Ciprofloxacin 400mg IV 12hrly

 

If known to have Pseudomonas spp. and sensitive to

Consider adding Gentamicin IV as per protocol instead of Vancomycin

Notes

Ensure sputum and atypical pneumonia screen (if appropriate) sent ASAP

If there is treatment failure/relapse check microbiology results, seek senior clinical review +/- D/W microbiology

Treat for 14 days