CAP (moderate severity) - CURB 65 Score 2

First Line

Amoxicillin 500mg-1g PO 8 hourly

PLUS EITHER

Doxycyline 200mg PO STAT, then 100mg daily

or

Clarithromycin 500mg PO 12 hourly

(Eyrthomycin 500mg PO 6 hourly in pregnancy)

 

 

If oral route is compromised:

Amoxicillin 500mg-1g IV 8 hourly AND Clarithromycin 500mg IV 12 hourly

Penicillin Allergy

Doxycycline 200mg PO STAT, then 100mg daily

or

Clarithromycin 500mg PO 12 hourly

(Erythromycin 500mg 6 hourly PO in pregnancy)

 

If oral route compromised:

Clarithromycin 500mg IV 12 hourly

Notes

Taker blood and sputum cultures.

Review travel history and animal (especially birds) exposure and consider investigation for atypical pathogens.

Treatment duration - 5 days