CAP - CURB 65 Score 2

First Line

Amoxicillin 500mg-1g tds PO

PLUS EITHER

Doxycyline 200mg stat then 100mg od PO

or

Clarithromycin 500mg bd PO

If oral route is compromised

Amoxicillin 500mg-1g IV 8 hourly AND Clarithromycin 500mg IV 12 hourly

Penicillin Allergy

Levofloxacin 500mg bd PO

 If oral route compromised

IV Levofloxacin 500mg bd IV

Notes

Send sputum for culture and sensitivity

Minimum duration of treament - 7 days

For patients who have had adequate treatment with recommended antimicrobials and not responded - see CURB 65 score ≥ 3 PO/IV options