Lower UTI - female (not pregnant)

First Line

Trimethoprim 200 mg bd PO

or

*Nitrofurantoin MR 100mg bd PO

* Nitrofurantoin is contra-indicated in patients with an eGFR < 45ml/min however a short course (3-7 days) may be used with caution in patients with an eGFR 30-44ml/min with suspected or proven multidrug resistant pathogens. Toxic plasma concentrations can occur particularly in the elderly causing adverse effects eg neuropathy, blood dyscrasias

Notes

DO NOT USE AMOXICILLIN ALONE UNLESS CULTURE + SENSTIVITIES SUPPORT

Ciprofloxacin should not be used first line

Send urine for C+S

3-day course.