Pyrexia in Labour / Maternal Sepsis

First Line

Co-amoxiclav 1.2g IV 8 hourly  +/- Gentamicin IV as per protocol

Escalation

 Piperacillin4g/Tazobactam 500mg IV 8 hrly  +/- Gentamicin IV as per protocol

Review daily with microbiology results and de-escalate if possible

Penicillin Allergy

Ceftriaxone 2g IV daily  AND Metronidazole 500mg IV 8 hourly +/- Gentamicin IV as per protocol

If anaphylaxis to penicillin

Vancomycin IV as per protocol AND Gentamicin IV as per protocol AND Metronidazole 500mg IV 8 hourly

Notes

Send blood cultures  and other relevant samples

Check previous / recent microbiology results for guidance

Check previous MRSA status

If there is treatment failure/relapse check microbiology results, seek senior clinical review +/- D/W microbiology