Diabetic Foot Infection/Diabetic foot ulcer

Micro-organism

Diabetic Foot Infection/Diabetic foot ulcer

Duration

Treat for 5 -7 days (mild to moderate) 10 – 14 days if severe

Mild

PO Flucloxacillin 1g four times daily

or

if penicillin allergy Doxycycline 100mg twice daily

Moderate

PO Co-Amoxiclav 625mg 8 hourly or IV 1.2g 8 hourly (375mg if low body weight )

 

Allergy (no previous antibiotics )

PO Clindamycin 300-450mg 6 hourly or IV 900mg 8 hourly

 

Previous antibiotics:

IV Ciprofloxacin 400mg 12 hourly +

IV Metronidazole 500mg 8 hourly.

 

Add Vancomycin if MRSA suspected.

Severe

No previous antibiotics

Iv Co-Amoxiclav 1.2g 8 hourly

+/-  IV Gentamicin

 

Previous antibiotics

 IV Piperacillin / Tazobactam 4.5g TID

Add  IV Vancomycin if MRSA suspected.

 

Allergy

IV Ciprofloxacin 400mg 12 hourly +

IV Metronidazole 500mg 8 hourly

Add IV Vancomycin if MRSA suspected